As internet speeds become faster, and computers become more powerful more and more software is moving to the cloud. Less than 5 years ago SculptGL would have been almost impossible, but in todays world Fully functional, 3d workflow is coming to your browser. Right now this software runs at peak performance in Chrome, and with limited vertices limited to 65536 in Firefox 22. In Firefox 24 that limit will be gone though.
SculptGL is a web sculpting application, powered by WebGL and JavaScript. It features dynamic and adaptive topological tools for sculpting. Adaptive sculpting enables changes in the topological genus which allows the user to create holes and merges on the model. The software looks promising, and it looks like this is the wave of the future. Even 3D giant Autodesk is jumping on the band wagon.